Griseofulvin is an antifungal
antibiotic. It inhibits cell division and DNA production of the
fungi. It is active against the common dermatophytes, including
some species of Epidermophyton, Microsporum, or Trichophyton.
Griseofulvin is used in the treatment of infections of the
scalp, hair, nails and skin which do not respond to topical
Griseofulvin may also be beneficial in treating infections of the soles of the feet, palms of the hands, and the nails.
Each tablet contains Griseofulvin 125mg
The usual dosage for adults is 500mg to 1g daily in single or
divided doses Children may be given 10mg per kg body-weight
daily. The duration of treatment could be 2 to 6 weeks for
infections of the hair and skin, up to 6 months for infections
of the fingernails, and 12 months or more for infections of the
toenails. Griseofulvin is best given with or after meals.
Griseofulvin is contraindicated in patients with severe liver disease or systemic lupus erythematosus (a systemic disease whereby the bodyï¿½s immune system attacks the bodyï¿½s own cells). Griseofulvin is also contraindicated in pregnancy. Women should not become pregnant during or within 1 month of stopping Griseofulvin treatment. For similar reasons, men receiving Griseofulvin should not father children within 6 months of treatment.